Diabetes mellitus can be cured by early detection and diabetes manifestation can be prevented. Genetic factors are responsible for the onset of type 2 diabetes, and fat deposits in the liver (and muscles), for example, can also further promote it. In addition, the biomarker intact proinsulin can be used independently to evaluate cardiovascular risk.

Type 2 diabetes is an epidemically growing disease worldwide. The latest estimations assume that approximately every 3rd adult, e.g. in the USA, will be impacted in the next 15 years. Because diabetes fundamentally damages the human body from head to toe, the individual effect of triggering various diseases and suffering is one of the major challenges of this time.

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BelDIA PRE offers a simple and so far unprecedented possibility to prevent the development of type 2 diabetes with all its sequelae by up to 50% with consistent adherence to lifestyle changes by early detection. The timely prophylaxis of elevated blood sugar, with all its harmful effects on almost all organs of the body, is the result of the frequent use of BelDIA PRE. It is a screening test for everyone at all times.

The rapid test displays within 20 minutes if the patient has an elevated intact proinsulin level. The lateral-flow test provides a qualitative result (clear staining of the test line), with a reading device the result can be quantitatively read off the value of the intact proinsulin in pmol/l.

If the result is positive, the patient has to consult his or her physician, who may be able to carry out further diagnostic investigations (e.g. of the vascular status, blood lipids, liver, etc.) and provide therapeutic recommendations for regression of prediabetes. A laboratory analysis now has to determine exact values of the increased intact proinsulin in the blood. Diabetes mellitus can be treated if it is detected at an early stage and diabetes manifestation can be avoided.


The test is useful for the early diagnosis of type 2 diabetes. Various studies have shown that the increase of intact proinsulin in the blood allows a prediction of developing type 2 diabetes up to 5 years in the future. Intact proinsulin in the blood is a highly specific laboratory indicator of ß-cell dysfunction.

The test is set up to differentiate disease-related elevated levels (> 15 pmol/l after meals) from normal intact proinsulin levels. By a laboratory analysis now exact values of the increased, intact Proinsulins in the blood must be determined. Only about 2 drops of capillary blood (50 µL) are used.

For use by healthcare professionals only.

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